Examining the long-term effects of Garcinia cambogia on weight loss

A study published in the journal BMC Complementary and Alternative Medicine has examined the effects of the treatment of garcinia cambogia and glucomannan on long-term weight loss in people who are overweight or obese. The study authors found that both treatments reduced weight and improved lipid and glucose blood profiles of the study participants.

• Researchers from the University of Cordoba in Spain recruited 214 overweight or obese people to participate in the study.
• The research team administered the study participants with 500 milligrams (mg) of garcinia cambogia and glucomannan twice a day for six months.
• They also assessed the participants’ weight, fat mass, visceral fat, basal metabolic rate, and lipid and glucose blood profiles before and after the treatment. Some patients were carriers of polymorphisms PLIN4 -11482G > A-, fat mass and obesity-associated (FTO) -rs9939609 A/T- and β-adrenergic receptor 3 (ADRB3) -Trp64Arg.
• Results revealed that the administration of garcinia cambogia and glucomannan caused weight loss by decreasing fat mass, visceral fat, lipid, and blood glucose profiles and increasing basal metabolic rate.
• In addition, the treatment with garcinia cambogia and glucomannan did not produce any adverse effect.
• However, the presence of PLIN4, FTO, Trp64Arg polymorphisms might hamper the beneficial effects of the treatment in some degree. Because of this, the study authors suggested future studies need to focus on the presence of these polymorphisms to get a better understanding of the treatment.

The findings of the study indicated that the treatment of garcinia cambogia and glucomannan were effective in reducing weight and enhancing lipid and glucose blood profiles in people who are overweight or obese.

For the full text of the study, go to this link.

Journal Reference:

Maia-Landim A, Ramirez JM, Lancho C, Poblador MS, Lancho, JL. LONG-TERM EFFECTS OF GARCINIA CAMBOGIA/GLUCOMANNAN ON WEIGHT LOSS IN PEOPLE WITH OBESITY, PLIN4, FTO AND TRP64ARG POLYMORPHISMS. BMC Complementary and Alternative Medicine. 2018; 18(26). DOI: https://doi.org/10.1186/s12906-018-2099-7